Serious Side Effects — Seek Immediate Medical Attention If:

Call 911 or go to the nearest emergency department if you experience:

• Thyroid C-cell tumors: Lump in the neck, hoarseness, difficulty swallowing, or shortness of breath.
• Pancreatitis: Severe, persistent abdominal pain (may radiate to the back) with or without vomiting.
• Gallbladder disease: Upper abdominal pain, jaundice (yellow skin or eyes), fever, or pale stools.
• Low blood sugar (hypoglycemia): Shakiness, sweating, dizziness, confusion, or rapid heartbeat — especially when used with insulin or sulfonylureas.
• Kidney injury or dehydration: Caused by severe nausea, vomiting, or diarrhea. Stay hydrated.
• Severe gastrointestinal reactions: Persistent or severe nausea, vomiting, or constipation.
• Severe allergic reaction: Swelling of the face, lips, tongue, or throat; rash or itching; trouble breathing; or fainting.
• Vision changes: Especially if you have diabetic retinopathy.
• Increased heart rate: Report sustained or unexplained racing heartbeat.
• Mood changes or suicidal thoughts: Contact your provider immediately if you experience new or worsening mental-health symptoms.
• Pulmonary aspiration during anesthesia: Inform your provider if you are scheduled for surgery requiring sedation or general anesthesia, as delayed gastric emptying may increase aspiration risk.

Never share your injection pen with others — sharing can spread infection.

Common Side Effects

The most frequently reported side effects of Wegovy include:

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Abdominal pain or discomfort
• Headache
• Fatigue
• Indigestion (dyspepsia)
• Dizziness
• Bloating (abdominal distension)
• Belching
• Gas (flatulence)
• Heartburn (GERD)
• Stomach infection (gastroenteritis)
• Low blood sugar in patients with type 2 diabetes

Most side effects are mild to moderate and tend to improve over time. Contact your healthcare provider if symptoms persist.