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Azelaic Acid Cream 20% for Acne | Skin Treatment Option
Azelaic Acid Cream prices from $718.57
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What is Azelaic acid cream?
Azelaic acid cream 20% is a prescription topical treatment used for mild-to-moderate inflammatory acne vulgaris. It is applied directly to the skin and is intended for acne care rather than general cosmetic use. While its exact mechanism is not fully known, it is believed to help through effects on acne-related bacteria and pore-clogging processes.
- A prescription topical treatment for inflammatory acne vulgaris
- Used directly on acne-prone areas of the skin
- Intended for dermatologic use only
- Not approved on this label for rosacea, dark spots, or scars
- Designed for regular use as directed by a healthcare provider
How do I take Azelaic acid cream?
Azelaic acid cream 20% is generally applied as a thin film twice daily, in the morning and evening. The skin should be washed and patted dry before use, and the cream should be gently worked into the affected areas. It should only be used on the skin and kept away from the eyes, mouth, and other mucous membranes.
- Apply a thin film twice daily
- Wash and dry the skin before applying
- Gently massage into the affected areas
- Wash your hands after use
- Do not use with occlusive dressings or wrappings
What are the possible side effects?
Azelaic acid cream 20% can cause local skin reactions, especially where it is applied. Common side effects include itching, burning, stinging, or tingling. Some people may also notice redness, dryness, peeling, or irritation.
- Common reactions include itching, burning, stinging, or tingling
- Redness, dryness, peeling, or rash can occur
- Stop use and contact your provider if severe irritation or sensitivity develops
- Seek medical advice if you notice unusual changes in skin color
- Rinse with plenty of water if it gets into your eyes and contact a provider if irritation continues
For detailed information see Important Safety Information.
*Prescription products require an online consultation with a licensed healthcare provider who will determine if treatment is appropriate. Individual results may vary.
PRODUCT Prices
Azelaic Acid prices
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Azelaic Acid 20%
$718.57
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If appropriate, a doctor will issue a prescription. Treatment decisions are always made by the provider.
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Your medication is shipped from a licensed partner pharmacy and typically arrives in 1–2 business days.
Similar Treatments
*Prescription products require an online consultation with a licensed healthcare provider who will determine if treatment is appropriate. Images are for Illustration purposes only. Actual product and packaging may differ.
Topics
What is Azelaic acid cream used for?
Azelaic acid cream 20% is used for the topical treatment of mild-to-moderate inflammatory acne vulgaris. It is meant for acne care on the skin and should be used as part of a consistent treatment routine rather than as an occasional spot product. On this page, the supported use is limited to inflammatory acne vulgaris, so it should not be described as a treatment for unrelated cosmetic concerns.
- Used for inflammatory acne vulgaris
- Applied directly to acne-prone skin
- Intended for prescription dermatologic use
- Best understood as an acne treatment, not a cosmetic cream
- Use should follow provider instructions and the prescribed course
How does Azelaic acid cream work in acne-prone skin?
- The exact way it works is not fully known
- It may have activity against acne-related bacteria
- It may help normalize keratinization in the skin
- It may help reduce microcomedo formation
- It should not be described as a guaranteed or rapid-result treatment
How is Azelaic acid cream generally used?
Azelaic acid cream 20% is generally used twice daily, once in the morning and once in the evening. The skin should be washed and patted dry before application, and the cream should be applied as a thin film and gently but thoroughly massaged into the affected areas. It is for skin use only and should be handled carefully to avoid accidental use on sensitive tissues.
- Apply a thin film in the morning and evening
- Wash and pat dry the skin before use
- Gently massage into the affected areas
- Wash hands after applying
- Use on the skin only
- Do not use occlusive dressings or wrappings over treated areas
What should you expect when starting Azelaic acid cream?
Azelaic acid cream 20% should be used for the full period your provider recommends, because treatment response varies from person to person. The prescribing information notes that improvement occurs in the majority of patients with inflammatory lesions within four weeks, but how quickly that happens can depend on the individual and the severity of acne. That means expectation-setting should stay realistic and should not promise a fixed outcome.
- Improvement may happen within the first several weeks
- Response can vary by person and acne severity
- Regular use matters when evaluating progress
- Early local irritation can happen when treatment begins
- Treatment should be reassessed with a provider if progress is unclear
What skin reactions can happen while using Azelaic acid cream?
Azelaic acid cream 20% can cause local skin reactions where it is applied. The most commonly reported reactions include itching, burning, stinging, and tingling, and additional reactions such as redness, dryness, rash, peeling, irritation, dermatitis, or contact dermatitis have also been reported. This section should explain the general skin-tolerance picture without becoming a full adverse-event list.
- Itching, burning, stinging, or tingling can occur
- Redness or dryness may develop
- Peeling or irritation may happen in some users
- Rash or dermatitis-type reactions have been reported
- Ongoing or worsening symptoms should be reviewed with a provider
When should you be more careful while using Azelaic acid cream?
Extra care is important when using Azelaic acid cream 20% around sensitive areas or on already irritated skin. The cream should be kept away from the eyes, mouth, and other mucous membranes, and it should not be used with occlusive dressings or wrappings. The label also warns that temporary irritation may occur when it is applied to broken or inflamed skin, especially early in treatment.
- Avoid the eyes, mouth, and mucous membranes
- Do not cover treated skin with occlusive dressings
- Be cautious on broken or inflamed skin
- Rinse with water if accidental eye exposure happens
- Contact a provider if eye irritation does not go away
Who should talk with a provider before using Azelaic acid cream?
Some patients should speak with a provider before using Azelaic acid cream 20% so that safety concerns can be reviewed early. That includes people with known hypersensitivity to any component of the product, people who are pregnant or breastfeeding, and parents considering it for children under 12, since pediatric safety and effectiveness have not been established. The labeling also highlights the need to watch for pigment changes, especially in patients with dark complexions.
- Discuss use if you have had a prior sensitivity reaction
- Talk with your provider if you are pregnant or planning pregnancy
- Ask about use if you are breastfeeding
- Review pediatric use carefully for children under 12
- Report unusual skin-color changes promptly
What symptoms should make you stop Azelaic acid cream and get medical advice?
Azelaic acid cream 20% should be stopped and medically reviewed if it causes sensitivity, severe irritation, or irritation that does not settle down. The label also supports attention to possible allergic reactions and to abnormal changes in skin color. If the product gets into the eyes and irritation continues after rinsing, that should also prompt provider contact.
- Stop use if severe irritation develops
- Contact a provider if symptoms persist
- Watch for signs of sensitivity or allergic reaction
- Report unusual skin-color changes
- Seek guidance if eye irritation continues after rinsing
How should Azelaic acid cream be stored and accessed through a prescription process?
Azelaic acid cream 20% should be stored between 15° and 30°C (59° to 86°F), protected from freezing, and stored on its side as directed in the product labeling. It is a prescription medication, so access should be framed as part of a provider-reviewed process rather than as an automatic purchase. This section should stay operational and avoid making promises about approval or fulfillment.
- Store at 59° to 86°F (15° to 30°C)
- Protect the product from freezing
- Store the tube on its side
- Keep and use it according to the dispensing instructions
- Obtain it through a prescription-based process
FAQ
What should I do if I miss a dose of Azelaic acid cream?
If you miss a dose, apply it at your next scheduled time. There’s no need to apply extra cream to make up for the missed application. Using more than directed can increase irritation without improving results.
- Skip the missed dose and continue as planned
- Do not apply a double amount
- Focus on staying consistent going forward
- Use reminders if needed
What should I do if my skin burns, stings, or feels irritated with Azelaic acid cream?
Some irritation can happen, especially early in treatment. If the reaction becomes uncomfortable or continues, you may need to adjust or pause use.
- Consider stopping temporarily if irritation is strong
- Avoid adding other irritating products
- Restart only if your skin tolerates it
- Contact your provider if symptoms persist
If irritation is severe or does not improve, refer to the Important Safety Information and speak with your provider.
Can I use Azelaic acid cream on broken or inflamed skin?
Azelaic acid cream may cause more irritation when applied to broken or inflamed skin. It’s best to be cautious in these areas, especially when starting treatment.
If your skin is already irritated, applying the cream may increase discomfort. In that case, it’s reasonable to wait until the area has calmed down or to ask your provider how to proceed. If irritation worsens, stop use and seek guidance.
How long should I use Azelaic acid cream before I check back with my provider?
Azelaic acid cream is typically used over several weeks as part of a treatment plan. The prescribing information notes that many patients see improvement within a few weeks, but this can vary.
- Track your progress over time
- Stay consistent with your routine
- Reassess if you don’t see improvement after several weeks
- Do not stop treatment early without guidance
Your provider can help decide whether to continue or adjust your treatment.
Can I use more Azelaic acid cream if I want faster results?
Using more than prescribed will not make the medication work faster. It may increase the risk of irritation or side effects instead.
- More product does not improve results
- Overuse may lead to irritation
- Follow the prescribed amount
- Ask your provider before making changes
If you feel your treatment is not working as expected, your provider can review your plan.
Can I put Azelaic acid cream near my eyes, nose, or mouth?
No, Azelaic acid cream should not be applied to the eyes, inside the nose, or on the mouth. These areas are more sensitive and can become irritated.
- Avoid contact with eyes and eyelids
- Do not apply inside the nose or mouth
- Use only on external skin
- Rinse if accidental contact occurs
If irritation develops after exposure, contact your provider for advice.
What should I do if Azelaic acid cream gets into my eyes?
If the cream gets into your eyes, rinse them thoroughly with plenty of water right away. Most mild irritation should improve after rinsing.
If eye irritation continues after flushing with water, contact a healthcare provider. Ongoing discomfort should not be ignored and may require further evaluation.
Can I use Azelaic acid cream if I notice changes in my skin color?
Changes in skin color, including lightening in certain areas, have been reported. If you notice unusual changes, you should contact your provider.
- Monitor your skin for noticeable changes
- Report any new or unusual discoloration
- Do not ignore persistent changes
- Ask your provider before continuing use
This is especially important if the changes are unexpected or continue over time.
Can I use Azelaic acid cream if I’m pregnant or breastfeeding?
If you are pregnant, planning pregnancy, or breastfeeding, you should speak with your provider before using this medication. The prescribing information recommends using it only if clearly needed.
Your provider can help weigh the potential risks and benefits based on your individual situation. Do not start or continue treatment without guidance.
Can children use Azelaic acid cream?
The safety and effectiveness of Azelaic acid cream have not been established in children under 12 years of age. If you are considering use for a younger patient, consult a healthcare provider.
They can help determine whether this medication is appropriate or recommend alternatives based on age and medical history.
Do I need a prescription to get Azelaic acid cream on this platform?
Yes, Azelaic acid cream 20% is a prescription medication. A licensed provider must evaluate your condition before it can be prescribed.
- Complete a medical assessment
- A provider reviews your information
- A prescription may be issued if appropriate
- Medication is dispensed through a pharmacy
Approval depends on your individual health profile.
How should I store Azelaic acid cream at home?
Azelaic acid cream should be stored properly to maintain its effectiveness and safety.
- Store at 59°F–86°F (15°C–30°C)
- Protect from freezing
- Store the tube on its side
- Keep it in a safe place away from children
Can I use Azelaic acid cream after it expires?
It’s generally not recommended to use the cream after its expiration date. The product may not perform as expected.
- Check the expiration date regularly
- Do not use expired medication unless advised
- Dispose of expired products properly
- Replace if needed
When in doubt, it’s safer to use a new supply.
Can I drink alcohol while using Azelaic acid cream?
There are no specific warnings in the prescribing information about alcohol use with this topical medication. However, individual responses can vary.
- No direct interaction is listed in the label
- Monitor how your skin responds during treatment
- Avoid assumptions about safety in all situations
- Ask your provider if you have concerns
For personalized advice, consult your healthcare provider.
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References
Azelex (Azelaic Acid Cream 20%) – topical treatment for mild-to-moderate inflammatory acne vulgaris. / Source: NCBI
Link: https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=0d5269d5-6555-4d2c-bc3b-df862b014275 / Published: May 2004
H. Igde - MD
Clinical Expertise: Anesthesiology, Emergency Medicine, Urology, and Oncology
As a medical expert, Igde, MD has carefully reviewed the medical content on this page and confirmed that it is accurate and up to date with current medical knowledge.
For more information about the scope of the reviewed content and the role of our medical advisors, please visit our Medical Board page.
Last Update on 02/29/2026 | Next Information check will be on 08/29/2026
*All information presented on this page is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment. Prescription products are available only after an online consultation with a licensed U.S. healthcare provider who determines if treatment is appropriate. Individual results may vary. US Quick Health LLC does not sell or ship medications directly. All prescriptions are fulfilled by licensed U.S. pharmacies.
PRODUCT® is a registered trademark of PRODUCT OWNER (e.g. Pfizer Inc.) and is mentioned for reference and informational purposes only. US Quick Health LLC is not affiliated with, endorsed by, or sponsored by PRODUCT OWNER (e.g. Pfizer Inc.) or any other trademark owners.
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All trademarks and registered brand names are the property of their respective owners. US Quick Health is a telehealth coordination platform and does not operate as a pharmacy. No medications or medical products are directly sold or shipped by US Quick Health. All information provided on usquickhealth.com is for informational purposes only and does not constitute medical advice or a binding offer. Use of this platform is at your own risk and initiative. You are solely responsible for complying with the applicable laws in your jurisdiction. Our services are not intended for emergency medical situations. In case of an emergency, please dial 911.
Medical consultations are conducted by independent, licensed healthcare professionals. US Quick Health does not employ medical providers and does not interfere with clinical decisions. US Quick Health complies with HIPAA and ensures that all personal health information (PHI) is handled securely and in accordance with U.S. privacy laws. All prescriptions are fulfilled by licensed U.S. pharmacies. Company Name: US Quick Health, LLC | Business Address: STE 27345 W Sand Lake Rd, Suite 210, Office 2630, Orlando, FL 32819 | Support Email: [email protected] | General Inquiries: [email protected] | Phone: +1 (332) 223-0323 | Business Hours: 24/7
Popular
Support
About Us
Legal
© 2025 US Quick Health, LLC. All rights reserved.
All trademarks and registered brand names are the property of their respective owners. US Quick Health is a telehealth coordination platform and does not operate as a pharmacy. No medications or medical products are directly sold or shipped by US Quick Health. All information provided on usquickhealth.com is for informational purposes only and does not constitute medical advice or a binding offer. Use of this platform is at your own risk and initiative. You are solely responsible for complying with the applicable laws in your jurisdiction. Our services are not intended for emergency medical situations. In case of an emergency, please dial 911.
Medical consultations are conducted by independent, licensed healthcare professionals. US Quick Health does not employ medical providers and does not interfere with clinical decisions. US Quick Health complies with HIPAA and ensures that all personal health information (PHI) is handled securely and in accordance with U.S. privacy laws. All prescriptions are fulfilled by licensed U.S. pharmacies. Company Name: US Quick Health, LLC | Business Address: STE 27345 W Sand Lake Rd, Suite 210, Office 2630, Orlando, FL 32819 | Support Email: [email protected] | General Inquiries: [email protected] | Phone: +1 (332) 223-0323 | Business Hours: 24/7
