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Breztri Aerosphere® | COPD Triple Therapy Inhaler

Breztri Aerosphere® prices from $940

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What is Breztri Aerosphere® Inhaler?

Breztri Aerosphere® is a prescription inhaler used for the long-term maintenance treatment of COPD (chronic obstructive pulmonary disease). It’s designed to help keep airways open and reduce inflammation over time—but it’s not for asthma and not for sudden breathing attacks. Think of it as part of your daily routine to manage symptoms, not something you grab in an emergency.

  • Contains 3 medicines in one inhaler (ICS + LAMA + LABA)
  • Helps reduce inflammation and relax airway muscles
  • Used regularly to manage COPD symptoms over time
  • Not a rescue inhaler for sudden shortness of breath
  • Prescription-only treatment that requires provider evaluation

Breztri Aerosphere® is used as a scheduled daily inhaler, not on-demand. You inhale the medication through your mouth, typically twice a day, to help keep your breathing stable over time. It’s important to use it consistently—even if you’re feeling okay—since it works in the background to support your lungs.

  • Taken as an inhalation (metered-dose inhaler / MDI)
  • Usually used morning and evening (as prescribed)
  • Not meant for quick relief during breathing emergencies
  • Rinse your mouth after use to help prevent irritation
  • Do not take extra doses unless your provider tells you

Like all medications, Breztri Aerosphere® can cause side effects. Many people tolerate it well, but some may notice mild symptoms, especially when starting. There are also a few important warning signs to watch for that may need medical attention.

  • Common: cough, sore throat, upper respiratory infections
  • Possible: oral thrush (white patches in mouth), headache, muscle spasms
  • May increase risk of infections like pneumonia
  • Get medical help right away if breathing suddenly worsens after use
  • Contact a provider or take emergency care if you notice signs of allergic reaction (rash, swelling, trouble breathing)

For more detail refer to the Important Safety / Prescribing Information.

*Prescription products require an online consultation with a licensed healthcare provider who will determine if treatment is appropriate. Budesonide, glycopyrrolate, and formoterol fumarate are the active ingredients in Breztri Aerosphere®. Breztri Aerosphere® is a registered trademark of its respective owner and is mentioned for reference only. Individual results may vary.

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Breztri Aerosphere®
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Breztri Aerosphere® 160/9/4.8

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$940

$990

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Answer a few health questions online – your information will be reviewed by a licensed provider.

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Prescription by a doctor

If appropriate, a doctor will issue a prescription. Treatment decisions are always made by the provider.

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Your medication is shipped from a licensed partner pharmacy and typically arrives in 1–2 business days.

Similar Treatments

*Prescription products require an online consultation with a licensed healthcare provider who will determine if treatment is appropriate. Images are for Illustration purposes only. Actual product and packaging may differ.

Topics

Is Breztri Aerosphere® Inhaler used for asthma or COPD?

Breztri Aerosphere® is approved for the maintenance treatment of COPD, not asthma. That means it’s used to help manage long-term breathing symptoms in people with COPD, such as chronic bronchitis or emphysema. If you have asthma, this inhaler is not an approved treatment, and a provider will guide you toward more appropriate options.

  • Designed specifically for COPD symptom control over time
  • Not approved for asthma treatment
  • Not used for sudden breathing problems or attacks
  • Requires a prescription and provider evaluation
  • Your diagnosis matters—treatment depends on your condition
What does “triple therapy” mean in Breztri Aerosphere® Inhaler?

“Triple therapy” means Breztri combines three different types of medications in one inhaler, each working in a different way to support your breathing. Instead of using multiple inhalers, this approach simplifies treatment into one routine.

  • Inhaled corticosteroid (reduces airway inflammation)
  • Long-acting muscarinic antagonist (relaxes airway muscles)
  • Long-acting beta agonist (helps keep airways open)
  • Designed for daily, ongoing use—not quick relief
  • Combination approach targets multiple pathways in COPD
How can Breztri Aerosphere® Inhaler help with COPD maintenance?

Breztri is used as part of a long-term management plan for COPD. It works in the background to help keep your airways more open and reduce inflammation, which may support more stable breathing when used consistently.

  • Helps maintain airway openness over time
  • Supports symptom control as part of daily routine
  • Not intended to replace rescue inhalers
  • Works best when used consistently as prescribed
  • Individual response can vary—regular follow-up is important
How is Breztri Aerosphere® Inhaler usually used?

Breztri is taken as a scheduled inhaler, meaning you use it at the same times each day rather than only when symptoms appear. Following a consistent routine helps maintain its effect.

  • Inhaled through the mouth using an MDI device
  • Typically used twice daily (morning and evening)
  • Mouth rinsing after use is recommended
  • Do not exceed prescribed dose
  • Not for sudden symptom relief—use a rescue inhaler if needed
Why isn’t Breztri Aerosphere® Inhaler a rescue inhaler?

Breztri is not designed to act quickly during sudden breathing problems. Instead, it works gradually to support long-term airway stability. For sudden symptoms, a short-acting rescue inhaler is usually required.

  • Does not provide immediate relief during attacks
  • Should not be used in place of emergency medication
  • Using it incorrectly may delay proper treatment
  • Seek medical help if breathing worsens suddenly
  • Always keep your rescue inhaler accessible
What should I tell a provider before using Breztri Aerosphere® Inhaler?

Before starting Breztri, your provider needs a full picture of your health. Certain conditions may affect whether this inhaler is appropriate or how it should be used.

  • Heart conditions or high blood pressure
  • Diabetes or thyroid disorders
  • Bone health concerns (e.g., osteoporosis)
  • Eye conditions like glaucoma or cataracts
  • Urinary or prostate issues
  • Current infections or immune system concerns
Which medicines may interact with Breztri Aerosphere® Inhaler?

Some medications can interact with Breztri or increase the risk of side effects. It’s important to review everything you’re taking—including other inhalers—with your provider.

  • Other long-acting bronchodilators (LABAs)
  • Anticholinergic medications
  • Certain antifungal or HIV treatments
  • Medicines that affect heart rhythm
  • Over-the-counter or herbal supplements


Never start or stop medications without medical guidance.

How should Breztri Aerosphere® Inhaler be stored and handled?

Proper storage helps keep your inhaler working as intended. Breztri comes in a pressurized canister, so handling it correctly is important for safety and effectiveness.

  • Store at room temperature in a dry place
  • Keep away from heat, flame, or direct sunlight
  • Do not puncture or expose the canister to high temperatures
  • Keep in original packaging until use
  • Follow discard instructions based on label guidance


Check your inhaler regularly to ensure it’s within the usable timeframe.

How can I get Breztri Aerosphere® Inhaler through an online visit?

Breztri is a prescription-only medication, so you’ll need to be evaluated by a licensed provider. US Quick Health makes this process more convenient by allowing you to complete your consultation online.

  • Complete a medical questionnaire or virtual visit
  • A provider reviews your history and symptoms
  • Prescription is issued if appropriate
  • Medication is sent to a pharmacy or delivered
  • Not everyone will qualify—clinical review is required


Always use licensed platforms and follow provider instructions throughout treatment.

Important safety information

What you should know before using Breztri Aerosphere®?

Product Information Leaflet

More Safety or Product Information

FAQ

Can I use Breztri Aerosphere® Inhaler for an asthma attack?

No—Breztri is not designed for sudden breathing problems or asthma attacks. It works as a maintenance inhaler for COPD, meaning it helps over time when used regularly, not instantly.

  • It does not act fast enough for emergency relief
  • Using it during an attack may delay proper treatment
  • You should use a rescue inhaler for sudden symptoms


If you experience a sudden worsening of breathing, use your prescribed rescue medication and seek medical help if symptoms don’t improve. Always follow your provider’s emergency plan.

Breztri is not approved for asthma treatment. It is specifically indicated for COPD, and using it for asthma would be outside its approved use.

  • Your provider will choose a treatment based on your diagnosis
  • Asthma and COPD require different treatment approaches
  • Using the wrong inhaler may not control symptoms effectively


If you’re unsure about your diagnosis or current treatment, it’s best to speak with a healthcare provider before starting or switching medications.

If you miss a dose, take it as soon as you remember—unless it’s close to your next scheduled dose. In that case, skip the missed dose and continue your regular schedule.

  • Do not take two doses at once
  • Stay consistent with your daily routine
  • Set reminders if needed to avoid missed doses


Missing an occasional dose may happen, but regular use is important for long-term control. If you miss doses often, talk to your provider about ways to stay on track.

No—you should not take extra doses unless your provider tells you to. Breztri is not meant for quick symptom relief, and taking more than prescribed may increase the risk of side effects.

  • It won’t provide fast relief during sudden symptoms
  • Overuse may affect your heart or other systems
  • Use a rescue inhaler for immediate breathing issues


If you’re often feeling short of breath, your treatment plan may need adjustment.

Yes—rinsing your mouth after each use is recommended. This helps reduce the risk of developing oral thrush, a fungal infection that can occur with inhaled corticosteroids.

  • Rinse with water and spit it out (do not swallow)
  • Helps keep your mouth and throat healthy
  • Quick step that can prevent irritation


If you notice white patches, soreness, or discomfort in your mouth, let your provider know.

Yes—these two inhalers serve different purposes and are often used together as part of a treatment plan.

  • Breztri is for daily maintenance
  • Rescue inhalers are for sudden symptoms
  • Always keep your rescue inhaler nearby


Make sure your provider knows all the inhalers you’re using to avoid overlap or interactions. If you’re using your rescue inhaler frequently, it may be a sign your condition needs reassessment.

There’s no direct restriction on alcohol in the prescribing information, but it’s still a good idea to be cautious. Alcohol can affect your overall health and may interact with certain conditions or medications.

  • Monitor how your body responds
  • Avoid excess alcohol if you have underlying conditions
  • Check with your provider if unsure


If you notice unusual symptoms after drinking, or if you take other medications, it’s best to get personalized advice.

Most people can continue normal activities like driving, but it depends on how you personally react to the medication.

  • Be aware of symptoms like dizziness or palpitations
  • Avoid driving if you feel unwell after use
  • Give yourself time to understand how your body responds


If you experience side effects that affect focus or coordination, speak with your provider before continuing to drive.

Store your inhaler in a cool, dry place at room temperature. Because it’s a pressurized canister, it should be handled with care.

  • Keep away from heat, flames, and direct sunlight
  • Do not store in very hot environments (like cars)
  • Keep it in its original packaging until use


When traveling, avoid exposing it to extreme temperatures. Proper storage helps ensure the medication works as intended.

You should discard your inhaler based on the dose counter or the expiration timeline after opening, whichever comes first.

  • Do not use it once the counter reaches zero
  • Follow the discard date listed on the packaging
  • Even if it feels like there’s medication left, it may not deliver a full dose

Yes, especially if you’re using other inhalers with similar ingredients. Some combinations may increase the risk of side effects.

  • Avoid using multiple LABA or anticholinergic inhalers together unless prescribed
  • Always share your full medication list with your provider
  • Do not add or switch inhalers without guidance


Your provider will help you build a safe and effective treatment plan.

Some symptoms need immediate attention. While not common, it’s important to recognize warning signs early.

  • Sudden worsening of breathing after use
  • Signs of allergic reaction (swelling, rash, trouble breathing)
  • Chest pain or irregular heartbeat
  • Signs of infection like fever or persistent cough


If you’re unsure whether a symptom is serious, it’s always safer to check with a healthcare provider.

You should not stop using Breztri without speaking to your provider. Even if you feel better, the medication is working in the background to keep symptoms controlled.

  • Stopping suddenly may lead to worsening symptoms
  • Treatment plans are designed for long-term use
  • Your provider can guide any changes safely


If you’re thinking about stopping or switching treatments, discuss it first to avoid unnecessary risks.

Yes—Breztri is a prescription-only medication. A licensed healthcare provider must evaluate your condition before it can be prescribed.

  • Requires medical review (online or in-person)
  • Prescription ensures safe and appropriate use


US Quick Health can make this process more convenient, but a clinical decision is always required.

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Breztri Aerosphere® (Budesonide/Glycopyrrolate/Formoterol 160/9/4.8 mcg) – triple therapy inhaler (ICS + LAMA + LABA) used for maintenance treatment of COPD, combining anti-inflammatory, bronchodilator, and anticholinergic effects. / Source: NCBI

Link: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=71a5433dc-cb2b-43ea-b6df-c5b4177adc6c / Published: July 23, 2020

H. Igde - MD

Clinical Expertise: Anesthesiology, Emergency Medicine, Urology, and Oncology

As a medical expert, Igde, MD has carefully reviewed the medical content on this page and confirmed that it is accurate and up to date with current medical knowledge.

For more information about the scope of the reviewed content and the role of our medical advisors, please visit our Medical Board page.

Last Update on 02/29/2026 | Next Information check will be on 08/29/2026

*All information presented on this page is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment. Prescription products are available only after an online consultation with a licensed U.S. healthcare provider who determines if treatment is appropriate. Individual results may vary. US Quick Health LLC does not sell or ship medications directly. All prescriptions are fulfilled by licensed U.S. pharmacies. 

Breztri Aerosphere® is a registered trademark of AstraZeneca and is mentioned for reference and informational purposes only. US Quick Health LLC is not affiliated with, endorsed by, or sponsored by AstraZeneca or any other trademark owners.

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All trademarks and registered brand names are the property of their respective owners. US Quick Health is a telehealth coordination platform and does not operate as a pharmacy. No medications or medical products are directly sold or shipped by US Quick Health. All information provided on usquickhealth.com is for informational purposes only and does not constitute medical advice or a binding offer. Use of this platform is at your own risk and initiative. You are solely responsible for complying with the applicable laws in your jurisdiction. Our services are not intended for emergency medical situations. In case of an emergency, please dial 911.

Medical consultations are conducted by independent, licensed healthcare professionals. US Quick Health does not employ medical providers and does not interfere with clinical decisions. US Quick Health complies with HIPAA and ensures that all personal health information (PHI) is handled securely and in accordance with U.S. privacy laws. All prescriptions are fulfilled by licensed U.S. pharmacies. Company Name: US Quick Health, LLC | Business Address: STE 27345 W Sand Lake Rd, Suite 210, Office 2630, Orlando, FL 32819 | Support Email: [email protected] | General Inquiries: [email protected] | Phone: +1 (332) 223-0323 | Business Hours: 24/7

© 2025 US Quick Health, LLC. All rights reserved.

All trademarks and registered brand names are the property of their respective owners. US Quick Health is a telehealth coordination platform and does not operate as a pharmacy. No medications or medical products are directly sold or shipped by US Quick Health. All information provided on usquickhealth.com is for informational purposes only and does not constitute medical advice or a binding offer. Use of this platform is at your own risk and initiative. You are solely responsible for complying with the applicable laws in your jurisdiction. Our services are not intended for emergency medical situations. In case of an emergency, please dial 911.

Medical consultations are conducted by independent, licensed healthcare professionals. US Quick Health does not employ medical providers and does not interfere with clinical decisions. US Quick Health complies with HIPAA and ensures that all personal health information (PHI) is handled securely and in accordance with U.S. privacy laws. All prescriptions are fulfilled by licensed U.S. pharmacies. Company Name: US Quick Health, LLC | Business Address: STE 27345 W Sand Lake Rd, Suite 210, Office 2630, Orlando, FL 32819 | Support Email: [email protected] | General Inquiries: [email protected] | Phone: +1 (332) 223-0323 | Business Hours: 24/7