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Daliresp® (Roflumilast) Tablets | COPD Exacerbation Risk

Daliresp® prices from $792.60

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What are Daliresp® Tablets?

Daliresp® Tablets is a prescription medication used to help reduce the risk of flare-ups (exacerbations) in people with severe COPD linked to chronic bronchitis. It contains roflumilast, which belongs to a class of medicines called phosphodiesterase-4 (PDE-4) inhibitors. It is important to note that this medication is not approved for asthma treatment and is not designed to relieve sudden breathing symptoms.

  • Used for long-term management of severe COPD
  • Belongs to a class called PDE-4 inhibitors
  • Taken as an oral tablet (250 mcg or 500 mcg)
  • Not a bronchodilator and not for quick symptom relief
  • Typically supplied in packs such as 30 tablets

Daliresp® Tablets is taken by mouth, usually once daily, with or without food. Some patients may start on a lower dose before moving to the standard maintenance dose, depending on provider guidance. It’s important to take it consistently to support its intended effect over time.

  • Taken once daily at the same time each day
  • Swallowed as a tablet, with or without food
  • May begin with a lower starter dose before increasing
  • Should not be used for sudden breathing problems
  • Follow your provider’s instructions closely


Always use this medication exactly as prescribed and do not adjust your dose without medical advice.

Daliresp® Tablets may cause side effects, including digestive symptoms and changes in appetite or weight. Some side effects may require medical attention, especially if they are persistent or concerning.

  • Common: diarrhea, nausea, decreased appetite
  • Weight loss may occur during treatment
  • Headache, dizziness, or trouble sleeping
  • Flu-like symptoms or back pain
  • Monitor for changes in how you feel overall


Contact your provider if you notice ongoing weight loss or unusual symptoms. Seek medical help right away if you experience mood changes such as depression, anxiety, or thoughts of self-harm.

For detailed information refer to the Important Safety / Prescribing Information.

*Prescription products require an online consultation with a licensed healthcare provider who will determine if treatment is appropriate. Roflumilast is the active ingredient in Daliresp®. Daliresp® is a registered trademark of its respective owner and is mentioned for reference only. Individual results may vary.

PRODUCT Prices

Daliresp® prices

Quantity

Price

Daliresp® Roflumilast 250 mcg

Save $50

$792.60

$842.60

Daliresp® Roflumilast 500 mcg

Save $50

$792.60

$842.60

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Answer a few health questions online – your information will be reviewed by a licensed provider.

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Prescription by a doctor

If appropriate, a doctor will issue a prescription. Treatment decisions are always made by the provider.

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Discreet and fast delivery

Your medication is shipped from a licensed partner pharmacy and typically arrives in 1–2 business days.

Similar Treatments

*Prescription products require an online consultation with a licensed healthcare provider who will determine if treatment is appropriate. Images are for Illustration purposes only. Actual product and packaging may differ.

Topics

Is Daliresp® Tablets used for asthma or COPD?

Daliresp® Tablets is approved for use in people with severe COPD associated with chronic bronchitis, particularly those who have a history of flare-ups. Even though you may be researching it under asthma treatments, it is not approved for asthma management based on current prescribing information.

  • Designed for COPD, not asthma
  • Used to help reduce flare-ups in specific COPD patients
  • Not part of standard asthma treatment plans
  • Should only be used for its approved indication
  • Your provider will determine if it’s appropriate


If you have asthma, your provider will typically recommend other treatments specifically approved for that condition.

When might a provider prescribe Daliresp® Tablets?

Daliresp® Tablets is usually considered for patients with more advanced COPD, especially when flare-ups continue despite other treatments. It is often part of a broader management plan.

  • Used in severe COPD with chronic bronchitis
  • Typically prescribed after evaluating symptom history
  • May be added alongside other COPD medications
  • Focused on reducing risk of exacerbations
  • Not used as a first-line treatment


Your provider will assess your history and symptoms before recommending this medication.

How does Daliresp® Tablets help reduce COPD flare-up risk?

Daliresp® Tablets works by targeting inflammation in the body through a specific pathway. It reduces activity in certain cells involved in inflammation, which may help lower the risk of COPD flare-ups over time.

  • Helps reduce inflammation linked to flare-ups
  • Works gradually with consistent use
  • Not designed for immediate symptom relief
  • Supports long-term disease management
  • Requires daily use for intended effect


Because it works over time, it’s important to take it consistently as prescribed.

How do people usually take Daliresp® Tablets?

Daliresp® Tablets is taken by mouth once daily. Some patients may begin with a lower dose before moving to the full maintenance dose, depending on how they tolerate the medication.

  • Taken once daily at a consistent time
  • Swallowed as a tablet
  • Can be taken with or without food
  • Lower starter dose may be used initially
  • Follow provider instructions carefully


Do not adjust your dose or schedule without guidance from your provider.

Can Daliresp® Tablets help with sudden breathing symptoms?

Daliresp® Tablets is not intended for sudden breathing problems. It does not act as a bronchodilator and will not provide immediate relief during a flare-up or breathing emergency.

  • Not for acute symptom relief
  • Does not replace rescue inhalers
  • Works over time, not instantly
  • Sudden symptoms require fast-acting medication
  • Seek urgent care if symptoms worsen quickly


Always keep your prescribed rescue medication available if needed.

What should patients know about mood, sleep, or behavior changes?

Daliresp® Tablets may be associated with changes in mood, behavior, or sleep. These can include anxiety, depression, or sleep disturbances in some patients.

  • Watch for changes in mood or behavior
  • Sleep problems or restlessness may occur
  • Report unusual thoughts or feelings
  • Important for both patients and caregivers to monitor
  • Stop medication and contact a provider if symptoms appear


For complete safety details, refer to the Important Safety Information and prescribing information.

Why does weight monitoring matter with Daliresp® Tablets?

Weight loss has been reported in patients taking Daliresp® Tablets. Because of this, regular weight monitoring is recommended during treatment.

  • Weight decrease may occur during use
  • Monitor weight regularly
  • Report unexplained or ongoing weight loss
  • Your provider may adjust treatment if needed
  • Important for long-term safety


If you notice significant changes in weight, contact your provider for guidance.

Who should talk to a provider before using Daliresp® Tablets?

Before starting Daliresp® Tablets, certain health conditions and factors should be discussed with your provider to ensure safe use.

  • History of liver problems
  • Mood or mental health concerns
  • Unexplained weight loss
  • Pregnancy or breastfeeding
  • Current medications or supplements


Providing full medical information helps your provider decide if this medication is appropriate for you.

What medicines may interact with Daliresp® Tablets?

Some medications can affect how Daliresp® Tablets works or increase the risk of side effects. It’s important to review all medications with your provider.

  • Certain enzyme-inducing medications may reduce effectiveness
  • Some medications may increase side effects
  • Include prescription and over-the-counter drugs
  • Also mention supplements or herbal products
  • Your provider will assess potential interactions


Always check with your provider before starting or stopping other medications.

Important safety information

What you should know before taking Daliresp®?

Product Information Leaflet

More Safety or Product Information

FAQ

How should Daliresp® Tablets be stored and handled?

Proper storage helps maintain the effectiveness of Daliresp® Tablets. Always follow the instructions provided with your medication.

  • Keep in original packaging
  • Store at room temperature
  • Protect from moisture
  • Keep out of reach of children
  • Check expiration dates regularly

Daliresp® Tablets is not approved for the treatment of asthma. It is specifically used for certain patients with severe COPD linked to chronic bronchitis.

  • Not indicated for asthma treatment
  • Designed for COPD-related flare-up prevention
  • Other medications are typically used for asthma
  • A provider can recommend appropriate options


If you have asthma, speak with your provider about treatments that are specifically approved for your condition.

No, Daliresp® Tablets is not a rescue medication and should not be used for sudden breathing problems.

  • Does not provide immediate relief
  • Not a bronchodilator
  • Works over time, not instantly
  • Keep rescue medication available if prescribed

If you miss a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one and continue your regular schedule.

  • Do not take two doses at the same time
  • Stay consistent with your dosing routine
  • Occasional missed doses can happen
  • Use reminders if needed

Yes, Daliresp® Tablets can be taken with or without food, depending on your preference.

  • No specific food restrictions
  • Can be taken at any time of day
  • Choose a routine that works for you

There are no specific alcohol restrictions listed in the prescribing information. However, alcohol may affect how you feel overall, especially regarding mood or liver health.

  • No direct interaction listed
  • Alcohol may worsen mood or sleep changes
  • Important if you have liver concerns
  • Discuss with your provider if unsure

Most people can continue normal activities, including driving, while taking Daliresp® Tablets. However, some may experience dizziness or other symptoms.

  • Be aware of how your body responds
  • Avoid driving if you feel unwell
  • Monitor for dizziness or fatigue
  • Safety should come first


If symptoms affect your alertness, wait until you feel stable before driving.

Some patients may begin treatment with a lower dose to help their body adjust before moving to the full dose.

  • 250 mcg may be used as a starter dose
  • Helps improve tolerability
  • Not the long-term maintenance dose
  • Your provider will guide dose changes


Always follow your provider’s instructions when starting or adjusting your dose.

No, you should not increase your dose on your own. Changes to your medication should always be guided by your provider.

  • Higher doses may increase side effects
  • Your provider will assess your symptoms
  • Adjustments may involve other treatments
  • Follow medical guidance closely


If symptoms worsen, contact your provider instead of changing your dose.

Daliresp® Tablets may cause changes in mood, behavior, or sleep in some patients. It’s important to be aware of these symptoms.

  • Anxiety, depression, or irritability
  • Trouble sleeping or unusual dreams
  • Changes in behavior or thinking
  • Thoughts of self-harm


If you notice any of these, stop taking the medication and contact your provider right away.

Weight loss has been reported in some patients taking Daliresp® Tablets, so regular monitoring is recommended.

  • Check your weight regularly
  • Watch for unexplained weight loss
  • Report ongoing changes to your provider
  • May require adjustment of treatment

“30 tablets” refers to the number of pills included in one package. It does not necessarily mean a 30-day supply.

  • Each tablet is one dose
  • Duration depends on your prescription
  • Some patients may use it daily
  • Follow your provider’s instructions


Your provider will determine how long your medication supply should last.

Yes, Daliresp® Tablets is a prescription medication and must be prescribed by a licensed healthcare provider.

  • Not available over the counter
  • Requires medical evaluation
  • May be part of a long-term treatment plan


A Healthcare Provider will determine if this medication is appropriate for you.

Before starting Daliresp® Tablets, share your full medical history and current medications with your provider.

  • History of liver problems
  • Mood or mental health concerns
  • Recent or unexplained weight loss
  • Current medications or supplements
  • Pregnancy or breastfeeding status


Providing complete information helps your provider make a safe and informed decision.

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Daliresp® (Roflumilast) Tablets – Treatment to reduce the risk of COPD exacerbations in patients with severe COPD associated with chronic bronchitis. / Source: NCBI Link: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c9a1d0a8-581f-4f91-a2b8-f419192d0ebf

H. Igde - MD

Clinical Expertise: Anesthesiology, Emergency Medicine, Urology, and Oncology

As a medical expert, Igde, MD has carefully reviewed the medical content on this page and confirmed that it is accurate and up to date with current medical knowledge.

For more information about the scope of the reviewed content and the role of our medical advisors, please visit our Medical Board page.

Last Update on 02/29/2026 | Next Information check will be on 08/29/2026

*All information presented on this page is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment. Prescription products are available only after an online consultation with a licensed U.S. healthcare provider who determines if treatment is appropriate. Individual results may vary. US Quick Health LLC does not sell or ship medications directly. All prescriptions are fulfilled by licensed U.S. pharmacies. 

Daliresp® is a registered trademark of AstraZeneca and is mentioned for reference and informational purposes only. US Quick Health LLC is not affiliated with, endorsed by, or sponsored by AstraZeneca or any other trademark owners.

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All trademarks and registered brand names are the property of their respective owners. US Quick Health is a telehealth coordination platform and does not operate as a pharmacy. No medications or medical products are directly sold or shipped by US Quick Health. All information provided on usquickhealth.com is for informational purposes only and does not constitute medical advice or a binding offer. Use of this platform is at your own risk and initiative. You are solely responsible for complying with the applicable laws in your jurisdiction. Our services are not intended for emergency medical situations. In case of an emergency, please dial 911.

Medical consultations are conducted by independent, licensed healthcare professionals. US Quick Health does not employ medical providers and does not interfere with clinical decisions. US Quick Health complies with HIPAA and ensures that all personal health information (PHI) is handled securely and in accordance with U.S. privacy laws. All prescriptions are fulfilled by licensed U.S. pharmacies. Company Name: US Quick Health, LLC | Business Address: STE 27345 W Sand Lake Rd, Suite 210, Office 2630, Orlando, FL 32819 | Support Email: [email protected] | General Inquiries: [email protected] | Phone: +1 (332) 223-0323 | Business Hours: 24/7

© 2025 US Quick Health, LLC. All rights reserved.

All trademarks and registered brand names are the property of their respective owners. US Quick Health is a telehealth coordination platform and does not operate as a pharmacy. No medications or medical products are directly sold or shipped by US Quick Health. All information provided on usquickhealth.com is for informational purposes only and does not constitute medical advice or a binding offer. Use of this platform is at your own risk and initiative. You are solely responsible for complying with the applicable laws in your jurisdiction. Our services are not intended for emergency medical situations. In case of an emergency, please dial 911.

Medical consultations are conducted by independent, licensed healthcare professionals. US Quick Health does not employ medical providers and does not interfere with clinical decisions. US Quick Health complies with HIPAA and ensures that all personal health information (PHI) is handled securely and in accordance with U.S. privacy laws. All prescriptions are fulfilled by licensed U.S. pharmacies. Company Name: US Quick Health, LLC | Business Address: STE 27345 W Sand Lake Rd, Suite 210, Office 2630, Orlando, FL 32819 | Support Email: [email protected] | General Inquiries: [email protected] | Phone: +1 (332) 223-0323 | Business Hours: 24/7