Compounded Semaglutide for Weight Management

Weight Loss Treatment

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Important informationshow detailshide detailsCompounded semaglutide is not FDA-approved.

Compounded medications are not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness or quality before they are dispensed. Compounded semaglutide is prescribed only when a licensed provider determines it is appropriate for you, and it is prepared by a licensed U.S. compounding pharmacy.

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Your provider determines your dose and adjusts it over time. The price is the same whichever dose is prescribed.

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Next: a short medical questionnaire. A licensed provider reviews your answers and decides whether treatment is appropriate for you.

$179.99per month

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About

What is compounded semaglutide?

Compounded semaglutide is a prescription medication prepared by a licensed U.S. compounding pharmacy for an individual patient. Semaglutide is a GLP-1 receptor agonist used for weight management. It works like the GLP-1 hormone your body makes after eating: it can increase feelings of fullness, slow how quickly your stomach empties and help regulate blood sugar. These effects come from studies of FDA-approved semaglutide medicines and cannot be assumed to apply to compounded formulations.

Compounded semaglutide is prepared in combination with either glycine or niacinamide. Your provider determines which formulation is right for you.

Compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness or quality before they reach patients.

How do I take compounded semaglutide?

Compounded semaglutide is taken as an injection under the skin, usually once a week. Your provider sets your starting dose and how it changes over time based on your response and tolerability.

Injected under the skin (abdomen, thigh, or upper arm)
Usually taken once weekly on a consistent schedule
Can be used with or without meals
Injection sites should be rotated regularly
Follow the dosing instructions on your pharmacy label exactly

What are the possible side effects?

Side effects of semaglutide most often involve the digestive system and are more common when starting treatment or after a dose change.

Common: nausea, diarrhea, vomiting, constipation, abdominal pain, decreased appetite
Other possible: fatigue, reflux symptoms, injection site reactions
Risk of low blood sugar may increase when used with certain diabetes medications
Seek urgent care for severe abdominal pain, which may indicate pancreatitis
Contact a provider immediately for a lump in the neck or trouble swallowing

*Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness or quality. Compounded semaglutide is not a generic version of any brand-name medication. Prescription medications are provided only after an online consultation with a licensed healthcare provider who determines whether treatment is appropriate. No specific results are guaranteed, and individual responses to treatment may vary.

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Cancel a subscription at any time. Your next refill date is shown in your account; cancel by 11:59 p.m. Eastern Time the day before to skip it. Refills already approved, dispensed or shipped cannot be canceled or refunded.

Topics

1. Who is compounded semaglutide for?
2. What should I know before starting?
3. What results can I expect?
4. When should I call a healthcare provider right away?
5. How should I store compounded semaglutide?
6. How do I get compounded semaglutide prescribed?

Who is compounded semaglutide for?

It may be considered for adults who meet medical criteria for weight management. A licensed provider reviews your health history and decides whether it is appropriate.

Compounded medicines are intended for patients whose medical needs are not met by an FDA-approved product. FDA-approved Wegovy and Ozempic are available through the same consultation.

May be considered when an FDA-approved medicine is not suitable for you, as determined by your provider
Adults with BMI ≥30, or ≥27 with a weight-related condition
Used together with a reduced-calorie diet and physical activity
Requires a medical evaluation before starting
Not appropriate for everyone

What should I know before starting?

Your provider will check for conditions that make semaglutide unsafe or that need extra monitoring.

A personal or family history of medullary thyroid carcinoma (MTC) or MEN 2 rules it out
Discuss any past pancreatitis, gallbladder disease or severe stomach problems
Tell your provider about allergies, including to glycine or niacinamide
Do not use during pregnancy; tell your provider if you are planning a pregnancy or breastfeeding

What results can I expect?

No clinical trials have been published for compounded semaglutide, so results seen with Wegovy or other FDA-approved products cannot be used to predict how this formulation will work for you. Results vary from person to person. Discuss realistic goals, uncertainties and FDA-approved alternatives with your provider, who decides whether treatment is appropriate for you at all. Our guide is compounded semaglutide safe explains the evidence and what FDA warns about.

When should I call a healthcare provider right away?

Severe or persistent abdominal pain
Signs of an allergic reaction such as swelling or difficulty breathing
A lump in the neck or trouble swallowing
Ongoing vomiting or diarrhea leading to dehydration
Sudden vision changes or gallbladder-related symptoms

If serious symptoms occur, seek immediate medical care.

How should I store compounded semaglutide?

Follow the storage instructions on the label from the compounding pharmacy. Storage requirements for compounded medications can differ from those of other products.

Keep refrigerated unless your pharmacy label says otherwise
Do not freeze
Do not use if the liquid looks cloudy or discolored
Ask your pharmacist if you are unsure

How do I get compounded semaglutide prescribed?

Complete an online consultation
A licensed U.S. provider reviews your health history and eligibility
If appropriate, your provider chooses the formulation and dose
A licensed U.S. compounding pharmacy prepares and ships your medication
Your provider can adjust your plan as you go

FAQ

Is compounded semaglutide the same as a brand-name medication?

No. Compounded semaglutide is prepared by a compounding pharmacy for an individual patient. It is not FDA-approved and is not a generic version of any brand-name medication.

What is the difference between the glycine and niacinamide formulations?

Both contain semaglutide. They differ in the added ingredient, glycine or niacinamide. Your provider determines which formulation is right for you.

Do I choose my dose?

No. Your provider sets your starting dose and adjusts it over time. The price is the same whichever dose is prescribed.

What should I do if I miss a dose?

Follow the instructions from your provider and your pharmacy label. Do not take two doses at once to make up for a missed one.

Can I take it with birth control pills?

Severe vomiting or diarrhea can make birth control pills less effective. Tell your provider about any birth control you use.

Do I need insurance?

No. Pricing is cash-pay and shown before you order.

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Other Weight loss treatments

Sources

References

FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss. / Source: U.S. Food and Drug Administration (FDA) Link: https://www.fda.gov/drugs/drug-alerts-and-statements/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss

Compounding and the FDA: Questions and Answers. / Source: U.S. Food and Drug Administration (FDA) Link: https://www.fda.gov/drugs/human-drug-compounding/compounding-and-fda-questions-and-answers

Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1). / Source: New England Journal of Medicine, 2021 Link: https://pubmed.ncbi.nlm.nih.gov/33567185/

*All information presented on this page is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment. Prescription products are available only after an online consultation with a licensed U.S. healthcare provider who determines if treatment is appropriate. Individual results may vary. US Quick Health LLC does not sell or ship medications directly. All prescriptions are fulfilled by licensed U.S. pharmacies.

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