Xopenex HFA

LevalbuterolAsthma Relief Inhaler

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About

What is Xopenex® (Levalbuterol) Inhaler 45 mcg?

Xopenex® (levalbuterol) inhaler 45 mcg is a prescription rescue inhaler used to help open your airways when breathing becomes difficult. It’s commonly prescribed for people with asthma or similar conditions and may be used to treat or prevent episodes of airway tightening (bronchospasm). It belongs to a class of medicines called short-acting beta2-agonists, also known as bronchodilators.

  • Used to relieve or prevent breathing symptoms like wheezing or shortness of breath
  • Approved for adults and children aged 4 years and older
  • Helps relax the muscles around your airways
  • Delivered directly to the lungs through a metered-dose inhaler (MDI)
  • Not a replacement for long-term asthma control medications

How do I use Xopenex® inhaler?

Xopenex® inhaler is used by inhaling the medication through the mouthpiece so it can reach your lungs directly. It’s typically used when symptoms occur or as directed by your healthcare provider. Following proper inhaler technique and instructions is important to ensure the medication works effectively.

  • Shake the inhaler before each use
  • Prime the inhaler before first use or if it hasn’t been used for several days
  • Inhale through the mouth using the inhaler device
  • Clean the actuator regularly to prevent blockage
  • Keep track of remaining doses using the dose indicator

What are the possible side effects?

Xopenex® inhaler may cause side effects, and they can vary from person to person. Some are related to how the medication affects your body, while others may require medical attention. It’s important to monitor how you feel after using it.

  • Common effects include dizziness, headache, or throat irritation
  • You may notice a fast heartbeat or feel shaky
  • Cough, runny nose, or general discomfort may occur
  • Some people experience stomach upset or vomiting

Seek medical help or CALL 911 right away if you notice:

  • Sudden worsening of breathing immediately after use
  • Signs of an allergic reaction such as swelling, rash, or trouble breathing

If side effects feel severe or unusual, contact your healthcare provider promptly.

For more detailled information refer to the prescribing information.

*Prescription products require an online consultation with a licensed healthcare provider who will determine if treatment is appropriate. Levalbuterol is the active ingredient in Xopenex®. Xopenex® is a registered trademark of Sunovion Pharmaceuticals and is mentioned for reference only. Individual results may vary.

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Topics

  1. 1. Is Xopenex® HFA used for asthma symptoms or breathing flare-ups?
  2. 2. Is Xopenex® HFA a rescue inhaler or a daily asthma controller?
  3. 3. Who may be a candidate for Xopenex® HFA?
  4. 4. How should patients think about using Xopenex® HFA correctly?
  5. 5. When should a patient contact a healthcare provider urgently?
  6. 6. What health conditions should be discussed before using Xopenex® HFA?
  7. 7. What medicines should patients mention before using Xopenex® HFA?
  8. 8. How do cleaning, dose tracking, and expiration fit into everyday use?
  9. 9. How does the online prescription process work?

Is Xopenex® HFA used for asthma symptoms or breathing flare-ups?

Xopenex® HFA inhaler is used to help manage breathing symptoms when your airways become tight. It’s prescribed for people with asthma or similar conditions to treat or prevent bronchospasm. The goal is to help restore easier breathing during symptom episodes.

  • Used when symptoms like wheezing or shortness of breath occur
  • Helps prevent episodes of airway tightening
  • Designed for people with reversible airway conditions
  • Approved for adults and children aged 4+
  • Should be used based on your provider’s instructions

Is Xopenex® HFA a rescue inhaler or a daily asthma controller?

Xopenex® HFA is considered a rescue inhaler, meaning it’s used when symptoms happen rather than on a fixed daily schedule. It works to open your airways during breathing flare-ups but does not treat underlying inflammation.

  • Used for quick relief when breathing becomes difficult
  • Not a replacement for daily controller medications
  • May be part of a broader asthma treatment plan
  • Often used alongside long-term medications
  • Increased use may indicate worsening asthma

Who may be a candidate for Xopenex® HFA?

Xopenex® HFA inhaler may be prescribed for people experiencing bronchospasm due to asthma or similar airway conditions. A healthcare provider will determine if it’s appropriate based on your symptoms and medical history.

  • Suitable for adults and children aged 4 years and older
  • Used for reversible airway narrowing conditions
  • Requires a medical evaluation before use
  • Not appropriate for individuals with known hypersensitivity
  • Selection depends on your overall health profile

Your provider will evaluate whether this inhaler is the right fit for your situation.

How should patients think about using Xopenex® HFA correctly?

Using your inhaler correctly is important to ensure the medication reaches your lungs effectively. Following proper handling and preparation steps can help maintain consistent performance.

  • Shake the inhaler before each use
  • Prime it before first use or after not using it for several days
  • Inhale through the mouthpiece as directed
  • Clean the actuator regularly
  • Avoid spraying into your eyes

When should a patient contact a healthcare provider urgently?

Certain symptoms or changes in how your inhaler works may require immediate medical attention. These situations can signal that your condition is not well controlled.

  • Breathing becomes worse after using the inhaler
  • You need to use it more often than usual
  • The inhaler no longer provides expected relief
  • You notice signs of an allergic reaction
  • Symptoms feel more severe than usual

If any of these occur, contact your provider or seek urgent care or in emergency CALL 911. Refer to Important Safety Information for more details.

What health conditions should be discussed before using Xopenex® HFA?

Before starting Xopenex® HFA, it’s important to share your full medical history. Some conditions may affect how your body responds to the medication or require closer monitoring.

  • Heart conditions, including irregular heartbeat or high blood pressure
  • Seizure disorders
  • Thyroid problems
  • Diabetes
  • Pregnancy or breastfeeding
  • Sensitivity to similar medications

This helps your provider determine whether the inhaler is appropriate for you.

What medicines should patients mention before using Xopenex® HFA?

Some medications can interact with Xopenex® HFA or influence how it works. Always tell your provider about everything you’re taking.

  • Other inhalers or bronchodilators
  • Beta-blockers (often used for heart conditions)
  • Diuretics (water pills)
  • Digoxin
  • Certain antidepressants (MAOIs or tricyclics)
  • Any recent medication changes

Your provider will review your medications to help reduce potential risks.

How do cleaning, dose tracking, and expiration fit into everyday use?

Proper maintenance of your inhaler helps ensure it works when needed. Keeping track of usage and following basic care steps is important for reliability.

  • Clean the actuator regularly to prevent blockage
  • Keep track of doses using the dose indicator
  • Do not rely on sound or shaking to estimate doses
  • Follow instructions for disposal after the labeled number of uses
  • Store according to label instructions

How does the online prescription process work?

Xopenex® HFA inhaler is a prescription medication, so it requires approval from a licensed healthcare provider. US Quick Health allows this process to happen online while maintaining proper medical review.

  • You complete a health questionnaire
  • A licensed provider reviews your information
  • A prescription is issued only if appropriate
  • Medication is dispensed through a licensed pharmacy
  • Follow-ups may be required for refills

This ensures the medication is used safely and appropriately.

Important safety information

FAQ

Can I get Xopenex® HFA inhaler online with a prescription?

Yes, but you’ll need a licensed healthcare provider to review your information first. Telemedicine platforms make it more convenient, but they don’t skip the medical decision. A prescription is only issued if it’s appropriate for your condition.

  • Complete a short online medical questionnaire
  • A provider reviews your symptoms and history
  • A prescription may be issued if suitable
  • Medication is shipped through a licensed pharmacy

If your case requires more evaluation, the provider may recommend a different approach instead.

Is Xopenex® HFA the same as levalbuterol?

Yes, Xopenex® HFA is the brand name, and levalbuterol is the active ingredient. They refer to the same medication used to help open your airways during breathing symptoms.

  • Xopenex® HFA = brand name
  • Levalbuterol = active ingredient
  • Both are used for similar breathing conditions
  • Differences may include manufacturer or device design

Is Xopenex® HFA the same as albuterol?

No, they are closely related but not identical. Xopenex® contains levalbuterol, which is a specific form of albuterol. Both are used for similar breathing symptoms, but your provider chooses based on your needs.

  • Both are bronchodilators
  • Used for similar asthma-related symptoms
  • Not interchangeable without provider guidance
  • Selection depends on your medical history

Do I need to use Xopenex® HFA every day?

No, Xopenex® HFA is usually not taken on a fixed daily schedule. It’s typically used when symptoms occur or as directed by your provider.

  • Often used “as needed”
  • Not a replacement for long-term control medications
  • Frequency depends on your symptoms
  • May be part of a broader treatment plan

What should I do if Xopenex® HFA does not seem to help?

If your inhaler isn’t relieving symptoms as expected, it’s important to take that seriously. This may mean your condition is changing or the inhaler is not being used correctly.

  • Check if the inhaler is empty or blocked
  • Review your inhaler technique
  • Avoid increasing use without guidance

If symptoms continue or worsen, contact your healthcare provider or seek urgent care. Refer to Important Safety Information for more details.

Can I use Xopenex® HFA with other asthma medicines?

In many cases, Xopenex® HFA is used alongside other asthma medications, but this should always be guided by a healthcare provider.

  • Often combined with long-term controller medications
  • Important to share all medications you take
  • Some combinations may require monitoring

Do not adjust or combine medications on your own. Your provider will ensure your treatment plan is safe.

Can I drink alcohol while using Xopenex® HFA?

The prescribing information does not specifically prohibit alcohol, but alcohol may affect how your body responds or how you feel.

  • May increase dizziness or heart-related sensations
  • Effects vary from person to person
  • Consider how your body reacts

If you have concerns or underlying conditions, it’s best to discuss alcohol use with your provider.

Can I drive after using Xopenex® HFA?

Most people can continue normal activities after using the inhaler. However, some may experience side effects that affect focus or coordination.

  • Watch for dizziness or shakiness
  • Avoid driving if you feel unwell
  • Wait until you feel stable

If you notice unusual symptoms after use, give yourself time before driving or operating machinery.

What should I do if I miss a dose or forget to use Xopenex® HFA?

Since Xopenex® HFA is often used as needed, missing a dose may not apply in the same way as daily medications.

  • Do not double doses
  • Use only as directed
  • Resume normal use when needed

If your provider gave specific instructions, follow those or ask for guidance if you’re unsure.

How should I store my Xopenex® HFA inhaler?

Proper storage helps ensure your inhaler works when you need it. Follow the instructions provided with your medication.

  • Keep the inhaler clean and dry
  • Store according to label instructions
  • Avoid extreme conditions
  • Keep out of reach of children

How do I know when my Xopenex® HFA inhaler is empty?

Xopenex® HFA inhalers include a dose indicator to help you track usage. This is the most reliable way to know when it’s time for a replacement.

  • Check the dose counter regularly
  • Plan ahead for refills
  • Do not rely on sound or shaking

Using an empty inhaler may not deliver the medication properly.

When should I ask for a refill?

It’s best to request a refill before your inhaler runs out completely. This helps ensure you always have access when needed.

  • Monitor your remaining doses
  • Refill before reaching zero
  • Follow your provider’s refill process

Other Asthma treatments

Sources

References

Xopenex® HFA (Levalbuterol 45 mcg) - short-acting β2-agonist inhaler (MDI) used for treatment and prevention of bronchospasm in patients with reversible obstructive airway disease. / Source: NCBI

Link: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=70a35706-d7a8-4a48-98c6-1cab1c42fe8d / Published: November 10, 2023

Medically reviewed by

H. Igde - MD

Clinical Expertise: Anesthesiology, Emergency Medicine, Urology, and Oncology

Dr. Igde reviewed the medical information on this page for accuracy against current medical knowledge. This is an editorial, non-clinical review: it is not medical advice and does not create a doctor-patient relationship. Whether a treatment is appropriate for you is decided by an independent U.S. licensed provider.

For more information about the scope of the reviewed content and the role of our medical advisors, please visit our Medical Board page.

H. Igde - MD
Last updated on 02/28/2026Next information check will be on 01/29/2027

*All information presented on this page is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment. Prescription products are available only after an online consultation with a licensed U.S. healthcare provider who determines if treatment is appropriate. Individual results may vary. US Quick Health LLC does not sell or ship medications directly. All prescriptions are fulfilled by licensed U.S. pharmacies.

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