Perforomist

FormoterolCOPD Nebulizer Maintenance

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About

What is Perforomist® Nebulizer?

Perforomist® Nebulizer is a prescription inhalation solution used for the long-term maintenance treatment of airway narrowing in people with chronic obstructive pulmonary disease (COPD). It contains formoterol, a long-acting beta2-agonist (LABA) that helps keep airways open over time. It is important to know that this medication is not approved for treating asthma and is not meant for sudden breathing problems.

  • Used regularly to help manage ongoing COPD symptoms
  • Belongs to a class of medicines called LABAs
  • Delivered as a mist through a nebulizer device
  • Not a rescue medication for sudden breathing issues
  • Prescribed based on your provider’s evaluation

How do I use Perforomist® Nebulizer?

Perforomist® Nebulizer is taken by inhaling a mist through a nebulizer machine connected to an air compressor. It is typically used on a set schedule, such as morning and evening, to help maintain open airways throughout the day. It should always be used exactly as prescribed by your healthcare provider.

  • Inhaled through a nebulizer with a mouthpiece or mask
  • Usually taken twice daily, about 12 hours apart
  • Each dose comes in a pre-measured vial
  • Not intended for quick relief of symptoms
  • Do not mix with other medications unless directed

What are the possible side effects?

Like all medications, Perforomist® Nebulizer may cause side effects. Many are related to how the body responds to a long-acting bronchodilator, while others may involve the digestive system or general discomfort. Some reactions may need medical attention, especially if they feel severe or unusual.

  • Common: diarrhea, nausea, dry mouth, dizziness
  • Respiratory symptoms like throat irritation or cold-like symptoms
  • Trouble sleeping or feeling restless
  • Vomiting or mild chest discomfort
  • Monitor any new or worsening symptoms

Seek urgent medical care if you experience sudden worsening breathing after use or signs of an allergic reaction such as swelling, rash, or difficulty breathing.

For full detail refer to the full Important Safety / Prescribing Information

*Prescription products require an online consultation with a licensed healthcare provider who will determine if treatment is appropriate. Formoterol fumarate is the active ingredient in Perforomist®. Perforomist® is a registered trademark of its respective owner and is mentioned for reference only. Individual results may vary.

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Topics

  1. 1. Is Perforomist® Nebulizer used for asthma or COPD?
  2. 2. When might a provider prescribe Perforomist® Nebulizer?
  3. 3. How does Perforomist® Nebulizer help keep airways open?
  4. 4. How do people usually use Perforomist® Nebulizer?
  5. 5. Can Perforomist® Nebulizer be used for sudden breathing symptoms?
  6. 6. What should patients know about using too much Perforomist® Nebulizer?
  7. 7. What symptoms need urgent medical attention?
  8. 8. Who should talk to a provider before using Perforomist® Nebulizer?
  9. 9. Can Perforomist® Nebulizer be mixed with other nebulizer medicines?

Is Perforomist® Nebulizer used for asthma or COPD?

Perforomist® Nebulizer is FDA-approved for the long-term maintenance treatment of airway narrowing in people with COPD, including chronic bronchitis and emphysema. It is not approved for asthma, and that distinction is important because this medication works differently from standard asthma treatments.

  • Approved specifically for COPD-related symptoms
  • Not indicated as an asthma treatment
  • Use in asthma without certain companion therapies may increase risk
  • Your diagnosis determines if this medication is appropriate
  • Always confirm your treatment plan with your provider

When might a provider prescribe Perforomist® Nebulizer?

A provider may prescribe Perforomist® Nebulizer when ongoing breathing symptoms require consistent, long-term control. It is typically used as part of a maintenance plan rather than for occasional or sudden symptoms.

  • Used for persistent symptoms like wheezing or shortness of breath
  • Taken on a regular schedule, not just when symptoms appear
  • Often part of a broader treatment plan
  • Selected based on your health history and symptom pattern
  • Requires ongoing medical supervision

This medication is usually one piece of a larger strategy to manage chronic respiratory conditions.

How does Perforomist® Nebulizer help keep airways open?

Perforomist® Nebulizer contains a long-acting bronchodilator that helps relax the muscles around your airways. This allows air to move more freely in and out of the lungs over time when used consistently.

  • Targets airway muscles that tighten during breathing conditions
  • Helps maintain more open airways throughout the day
  • Designed for ongoing symptom control
  • Works gradually rather than instantly
  • Best results depend on regular use

It’s important to use it as prescribed to maintain its intended effect.

How do people usually use Perforomist® Nebulizer?

Perforomist® Nebulizer is used with a nebulizer machine that turns the liquid medication into a mist you inhale. It is generally taken on a fixed schedule to help maintain steady control of symptoms.

  • Inhaled through a mouthpiece or mask
  • Typically used twice daily, about 12 hours apart
  • Each dose comes in a single-use vial
  • Requires a compressor-based nebulizer system
  • Follow device cleaning and handling instructions

Consistency is key - using it at the same times each day helps maintain stable symptom control.

Can Perforomist® Nebulizer be used for sudden breathing symptoms?

Perforomist® Nebulizer is not intended for sudden breathing problems or emergency use. It is designed for maintenance, meaning it helps manage symptoms over time rather than providing quick relief.

  • Not suitable for acute breathing attacks
  • Slower onset compared to rescue medications
  • Sudden symptoms may require a different treatment
  • Your provider may prescribe a separate rescue inhaler
  • Severe symptoms need immediate medical attention

If your breathing suddenly worsens, seek medical care instead of relying on this medication.

What should patients know about using too much Perforomist® Nebulizer?

Using more Perforomist® Nebulizer than prescribed can increase the risk of side effects, especially those related to the heart and nervous system. It’s important to stick to your prescribed schedule.

  • Do not increase dose or frequency on your own
  • Avoid combining with other LABA medications unless directed
  • Overuse may lead to heart-related symptoms
  • More medication does not mean better control
  • Follow your provider’s exact instructions

If your symptoms are not controlled, talk to your provider rather than adjusting the dose yourself.

What symptoms need urgent medical attention?

Some symptoms may require immediate medical attention, especially if they suggest a serious reaction or worsening condition. Recognizing these early can help prevent complications.

  • Sudden worsening of breathing after use
  • Signs of allergic reaction like swelling or rash
  • Chest pain, rapid heartbeat, or feeling faint
  • Severe dizziness or unusual weakness
  • Difficulty breathing that does not improve

If any of these occur, seek urgent care. Additional safety details are available in the Important Safety Information

Who should talk to a provider before using Perforomist® Nebulizer?

Before starting Perforomist® Nebulizer, your provider needs a full picture of your health to determine if it’s appropriate for you. Certain conditions may increase risk or require closer monitoring.

  • Heart conditions or high blood pressure
  • Diabetes or thyroid disorders
  • Seizure history
  • Liver problems
  • Pregnancy or breastfeeding

You should also share all medications you are taking to help avoid potential interactions.

Can Perforomist® Nebulizer be mixed with other nebulizer medicines?

Perforomist® Nebulizer should not be mixed with other medications in the nebulizer unless specifically instructed. Its safety and effectiveness when combined with other drugs in the same chamber have not been established.

  • Do not mix medications on your own
  • Compatibility with other drugs is not guaranteed
  • Follow instructions from your provider or pharmacist
  • Use each medication as directed

If you are prescribed multiple nebulized treatments, your provider will guide you on how to take them safely.

Important safety information

FAQ

Can I use Perforomist® Nebulizer if I have asthma?

Perforomist® Nebulizer is not approved for asthma. It is labeled for long-term treatment of COPD, and using it in asthma without certain companion medications may increase risk. That’s why it’s important to follow a provider-guided treatment plan.

  • Not indicated as an asthma treatment
  • May carry specific risks in asthma patients
  • Your provider will choose the right therapy for your condition
  • Do not start or continue without medical guidance

If you’ve been prescribed this and have asthma, check with your provider to confirm it’s appropriate for you.

Is Perforomist® Nebulizer a rescue medication?

No, Perforomist® Nebulizer is not designed for immediate relief of sudden breathing symptoms. It is a maintenance medication used on a regular schedule to help manage symptoms over time.

  • Not for sudden breathing attacks
  • Does not replace a rescue inhaler
  • Works best when used consistently
  • Emergency symptoms need urgent care

If you experience sudden or severe breathing problems, seek medical help right away.

What should I do if I miss a dose of Perforomist® Nebulizer?

If you miss a dose, take it as soon as you remember - unless it’s close to your next scheduled dose. In that case, skip the missed one and continue with your regular schedule.

  • Do not take two doses at the same time
  • Keep your dosing routine consistent
  • Use reminders if needed
  • Occasional missed doses can happen

Can I use Perforomist® Nebulizer more often if my breathing feels worse?

No, you should not increase how often you use Perforomist® Nebulizer without medical advice. Worsening symptoms may mean your condition needs reassessment rather than more medication.

  • Increasing the dose may raise risk of side effects
  • More frequent use is not a substitute for proper treatment
  • Your provider may need to adjust your plan
  • Sudden worsening symptoms should be evaluated

If your breathing changes, contact your provider instead of adjusting your dose.

Can I mix Perforomist® Nebulizer with other nebulizer medications?

You should not mix Perforomist® Nebulizer with other medications in the nebulizer unless your provider specifically instructs you to do so. Its compatibility with other drugs has not been established.

  • Do not combine medications on your own
  • Mixing may affect safety or effectiveness
  • Follow professional guidance for multiple treatments
  • Ask your pharmacist if unsure

If you’re prescribed more than one nebulized medication, your provider will explain how to take them safely.

Can I eat or drink before using Perforomist® Nebulizer?

There are no specific food or drink restrictions associated with Perforomist® Nebulizer. You can generally use it regardless of meals.

  • No known food interactions
  • Can be used before or after eating
  • Stay hydrated if you experience dry mouth

If you have other health conditions or medications, your provider may give more personalized advice.

Can I drink alcohol while using Perforomist® Nebulizer?

There are no specific alcohol restrictions listed in the prescribing information. However, alcohol can affect how you feel and may interact with other conditions or medications.

  • No direct interaction listed in the PI
  • Alcohol may worsen certain symptoms in some people
  • Monitor how your body responds
  • Ask your provider if you’re unsure

If you notice unusual symptoms after drinking, it’s best to limit alcohol and discuss it with your provider.

Can I drive after using Perforomist® Nebulizer?

Most people can continue normal activities after using Perforomist® Nebulizer. However, if you feel dizzy or unwell, you should wait until you feel stable before driving.

  • Watch for dizziness or lightheadedness
  • Avoid driving if you feel impaired
  • Try using the medication at home first
  • Safety comes first

How long does one nebulizer treatment usually take?

A typical nebulizer session with Perforomist® Nebulizer takes several minutes, depending on your device and breathing pattern. The goal is to inhale the full dose as prescribed.

  • Usually takes around 5-10 minutes
  • Continue until the mist stops
  • Sit upright during use
  • Follow your device instructions

Taking your time ensures you receive the full dose correctly.

How should I store Perforomist® Nebulizer at home?

Perforomist® Nebulizer should be stored according to label instructions to keep it effective. Temperature and light exposure are important factors.

  • Store in the refrigerator when possible
  • Can be kept at room temperature for a limited time
  • Keep in foil pouch until ready to use
  • Protect from heat and light

Check the packaging for storage timelines and discard any unused medication as directed.

Do I need a prescription for Perforomist® Nebulizer?

Yes, Perforomist® Nebulizer is a prescription medication. You will need to be evaluated by a licensed healthcare provider before using it.

  • Not available over the counter
  • Requires a medical assessment
  • May be part of a long-term treatment plan
  • Follow-up care may be needed

Telemedicine services can help determine if this medication is appropriate for you.

What should I tell my provider before starting Perforomist® Nebulizer?

Before starting, share your full medical history and current medications. This helps your provider decide if Perforomist® Nebulizer is safe and appropriate for you.

  • Heart conditions or blood pressure issues
  • Diabetes or thyroid disorders
  • Seizure history
  • Pregnancy or breastfeeding
  • All medications and supplements

Clear communication helps reduce risks and ensures safer treatment.

What should I do if Perforomist® Nebulizer does not seem to control my symptoms?

If your symptoms are not well controlled, do not increase your dose on your own. This may signal that your condition needs reassessment.

  • Your provider may adjust your treatment plan
  • Additional medications may be needed
  • Worsening symptoms can indicate disease progression
  • Early action helps prevent complications

Other Asthma treatments

Sources

References

Perforomist® (Formoterol Fumarate) Inhalation Solution - Long-term maintenance treatment of bronchoconstriction in patients with COPD. / Source: NCBI Link: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fb2fe258-fe2e-47f6-8adf-ca75bf6f90af / Published: May 2019

Medically reviewed by

H. Igde - MD

Clinical Expertise: Anesthesiology, Emergency Medicine, Urology, and Oncology

Dr. Igde reviewed the medical information on this page for accuracy against current medical knowledge. This is an editorial, non-clinical review: it is not medical advice and does not create a doctor-patient relationship. Whether a treatment is appropriate for you is decided by an independent U.S. licensed provider.

For more information about the scope of the reviewed content and the role of our medical advisors, please visit our Medical Board page.

H. Igde - MD
Last updated on 02/28/2026Next information check will be on 01/29/2027

*All information presented on this page is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment. Prescription products are available only after an online consultation with a licensed U.S. healthcare provider who determines if treatment is appropriate. Individual results may vary. US Quick Health LLC does not sell or ship medications directly. All prescriptions are fulfilled by licensed U.S. pharmacies.

Perforomist® is a registered trademark of its respective owner and is mentioned for reference and informational purposes only. US Quick Health LLC is not affiliated with, endorsed by, or sponsored by the trademark owner of Perforomist® or any other trademark owners.

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