Daliresp

Daliresp® Tablets is a prescription medication used to help reduce the risk of flare-ups (exacerbations) in people with severe COPD linked to chronic bronchitis. It contains roflumilast, which belongs to a class of medicines called phosphodiesterase-4 (PDE-4) inhibitors. It is important to note that this medication is not approved for asthma treatment and is not designed to relieve sudden breathing symptoms.

• Used for long-term management of severe COPD
• Belongs to a class called PDE-4 inhibitors
• Taken as an oral tablet (250 mcg or 500 mcg)
• Not a bronchodilator and not for quick symptom relief
• Typically supplied in packs such as 30 tablets

Daliresp® Tablets is taken by mouth, usually once daily, with or without food. Some patients may start on a lower dose before moving to the standard maintenance dose, depending on provider guidance. It’s important to take it consistently to support its intended effect over time.

• Taken once daily at the same time each day
• Swallowed as a tablet, with or without food
• May begin with a lower starter dose before increasing
• Should not be used for sudden breathing problems
• Follow your provider’s instructions closely

Always use this medication exactly as prescribed and do not adjust your dose without medical advice.

Daliresp® Tablets may cause side effects, including digestive symptoms and changes in appetite or weight. Some side effects may require medical attention, especially if they are persistent or concerning.

• Common: diarrhea, nausea, decreased appetite
• Weight loss may occur during treatment
• Headache, dizziness, or trouble sleeping
• Flu-like symptoms or back pain
• Monitor for changes in how you feel overall

Contact your provider if you notice ongoing weight loss or unusual symptoms. Seek medical help right away if you experience mood changes such as depression, anxiety, or thoughts of self-harm.

For detailed information refer to the Important Safety / Prescribing Information.

Proper storage helps maintain the effectiveness of Daliresp® Tablets. Always follow the instructions provided with your medication.

• Keep in original packaging
• Store at room temperature
• Protect from moisture
• Keep out of reach of children
• Check expiration dates regularly

Daliresp® Tablets is not approved for the treatment of asthma. It is specifically used for certain patients with severe COPD linked to chronic bronchitis.

• Not indicated for asthma treatment
• Designed for COPD-related flare-up prevention
• Other medications are typically used for asthma
• A provider can recommend appropriate options

If you have asthma, speak with your provider about treatments that are specifically approved for your condition.

No, Daliresp® Tablets is not a rescue medication and should not be used for sudden breathing problems.

• Does not provide immediate relief
• Not a bronchodilator
• Works over time, not instantly
• Keep rescue medication available if prescribed

If you miss a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one and continue your regular schedule.

• Do not take two doses at the same time
• Stay consistent with your dosing routine
• Occasional missed doses can happen
• Use reminders if needed

Yes, Daliresp® Tablets can be taken with or without food, depending on your preference.

• No specific food restrictions
• Can be taken at any time of day
• Choose a routine that works for you

There are no specific alcohol restrictions listed in the prescribing information. However, alcohol may affect how you feel overall, especially regarding mood or liver health.

• No direct interaction listed
• Alcohol may worsen mood or sleep changes
• Important if you have liver concerns
• Discuss with your provider if unsure

Most people can continue normal activities, including driving, while taking Daliresp® Tablets. However, some may experience dizziness or other symptoms.

• Be aware of how your body responds
• Avoid driving if you feel unwell
• Monitor for dizziness or fatigue
• Safety should come first

If symptoms affect your alertness, wait until you feel stable before driving.

Some patients may begin treatment with a lower dose to help their body adjust before moving to the full dose.

• 250 mcg may be used as a starter dose
• Helps improve tolerability
• Not the long-term maintenance dose
• Your provider will guide dose changes

Always follow your provider’s instructions when starting or adjusting your dose.

No, you should not increase your dose on your own. Changes to your medication should always be guided by your provider.

• Higher doses may increase side effects
• Your provider will assess your symptoms
• Adjustments may involve other treatments
• Follow medical guidance closely

If symptoms worsen, contact your provider instead of changing your dose.

Daliresp® Tablets may cause changes in mood, behavior, or sleep in some patients. It’s important to be aware of these symptoms.

• Anxiety, depression, or irritability
• Trouble sleeping or unusual dreams
• Changes in behavior or thinking
• Thoughts of self-harm

If you notice any of these, stop taking the medication and contact your provider right away.

Weight loss has been reported in some patients taking Daliresp® Tablets, so regular monitoring is recommended.

• Check your weight regularly
• Watch for unexplained weight loss
• Report ongoing changes to your provider
• May require adjustment of treatment

“30 tablets” refers to the number of pills included in one package. It does not necessarily mean a 30-day supply.

• Each tablet is one dose
• Duration depends on your prescription
• Some patients may use it daily
• Follow your provider’s instructions

Your provider will determine how long your medication supply should last.

Yes, Daliresp® Tablets is a prescription medication and must be prescribed by a licensed healthcare provider.

• Not available over the counter
• Requires medical evaluation
• May be part of a long-term treatment plan

A Healthcare Provider will determine if this medication is appropriate for you.

Before starting Daliresp® Tablets, share your full medical history and current medications with your provider.

• History of liver problems
• Mood or mental health concerns
• Recent or unexplained weight loss
• Current medications or supplements
• Pregnancy or breastfeeding status

Providing complete information helps your provider make a safe and informed decision.

Daliresp® (Roflumilast) Tablets - Treatment to reduce the risk of COPD exacerbations in patients with severe COPD associated with chronic bronchitis. / Source: NCBI Link: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c9a1d0a8-581f-4f91-a2b8-f419192d0ebf