Loryna

Loryna is a prescription combined birth control pill containing drospirenone 3 mg and ethinyl estradiol 0.02 mg. It is FDA-approved to prevent pregnancy and has two additional approved uses in certain patients.

• Loryna contains a progestin and an estrogen.
• It mainly prevents pregnancy by stopping ovulation and also changes cervical mucus.
• It can treat PMDD symptoms when the patient has chosen an oral contraceptive for birth control.
• It can treat moderate acne in patients age 14 and older who have started having periods, can use oral contraceptives, and also want birth control.
• Loryna is not approved to treat ordinary PMS, and its effectiveness for PMDD beyond 3 menstrual cycles has not been evaluated.

Your healthcare provider will determine whether Loryna is appropriate for you.

Take one Loryna tablet by mouth every day at the same time, following the order shown on the blister pack. Each 28-day pack contains 24 active peach tablets followed by 4 white inactive tablets.

• Loryna can be taken with or without food.
• Take the tablets in the order shown on the package.
• Try to take your pill at the same time each day.
• Missing active pills or taking them incorrectly may reduce pregnancy protection.
• Specific instructions apply if you miss pills, vomit, have severe diarrhea, or are switching from another birth control method.

Follow the Patient Information that comes with your medication for detailed instructions. If you are unsure what to do after a missed pill or another dosing problem, contact your healthcare provider or pharmacist.

Common side effects reported with Loryna include headache or migraine, changes in menstrual bleeding, nausea or vomiting, breast pain or tenderness, and mood changes. Not everyone will have the same side effects, and this is not a complete list.

• Combined birth control pills can increase the risk of serious blood clots, heart attack, and stroke.
• Seek urgent medical care for sudden shortness of breath, severe chest pain, persistent leg pain, sudden vision problems, or sudden weakness, numbness, or trouble speaking.
• Contact your healthcare provider if you develop a significant new or worsening headache or migraine.
• People over age 35 who smoke cigarettes should not use Loryna because smoking further increases the risk of serious cardiovascular problems.

See the Important Safety Information and Prescribing Information for additional warnings, contraindications, and risks.

See Important Safety Information and full Prescribing Information: Here

Loryna requires a prescription, and your healthcare provider should review your health history before prescribing it. Tell them if you smoke or have a history of blood clots, migraines, high blood pressure, diabetes, kidney, liver or adrenal problems, breast cancer, or unexplained bleeding. Also mention pregnancy, breastfeeding, recent childbirth, upcoming major surgery, and every medicine or supplement you take. If Loryna is not appropriate for you, your provider can discuss another birth control option.

Drospirenone, one of the hormones in Loryna, can increase potassium levels. This is especially important if you have kidney, liver, or adrenal problems or take certain medicines that can also raise potassium. Examples include spironolactone, potassium supplements, some blood pressure medicines, and long-term daily NSAID treatment. Some patients taking these medicines may need a potassium blood test during their first treatment cycle. Tell your provider what you take rather than stopping or changing medicines on your own.

The instructions depend on how many active peach pills you miss and where you are in your pack. If you miss one active pill, take it as soon as you remember and take your next pill at the usual time; backup birth control is not required. Missing two or more active pills may require 7 days of backup contraception. Follow the Patient Information for the exact steps.

If you vomit within about 3 to 4 hours after taking Loryna, follow the instructions for a missed pill. Diarrhea may also make your birth control less effective. The Patient Information advises using backup birth control, such as condoms, until you have checked with your healthcare provider if vomiting or diarrhea affects your pills.

A missed period does not always mean you are pregnant, but pregnancy may need to be ruled out. Contact your healthcare provider if you miss a period after not taking your pills correctly, think you may be pregnant, or miss two periods in a row even though you took Loryna as directed. Stop Loryna if pregnancy is confirmed.

Loryna contains estrogen, which may decrease the amount of breast milk you produce. The FDA-approved labeling recommends considering another birth control method while breastfeeding until you are ready to stop breastfeeding. Tell your healthcare provider if you recently gave birth or are breastfeeding so they can help determine which contraceptive option is appropriate for you.

Yes. Loryna can be taken without regard to meals. The key is to take one tablet at about the same time each day and follow the pills in the order shown on your pack. If nausea is an issue, the labeling notes that taking it after an evening meal or at bedtime is an option.

LORYNA - drospirenone and ethinyl estradiol tablets kit / Source: DailyMed

Link: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=da872266-d5f2-35df-096e-341f58d93427 / Published: July 10, 2023